Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590837 | 0.99 | HRH3 (0.45) | MEN1KMT2AHRH3 | |
| SCHEMBL4590551 | 0.99 | HRH3 (0.45) | MEN1KMT2AHRH3 | |
| SCHEMBL4590031 | 0.91 | HRH3 (0.43) | MEN1KMT2AHRH3 | |
| SCHEMBL4590516 | 0.91 | HRH3 (0.46) | HRH3KCNH2SLC6A2SLC6A4 | |
| SCHEMBL4590678 | 0.86 | HRH3 (0.35) | MEN1KMT2AHRH3HRH2HRH1 | |
| SCHEMBL4591158 | 0.85 | HRH3 (0.46) | HRH3KCNH2MCHR1SLC6A2SLC6A4 | |
| SCHEMBL4590546 | 0.85 | KCNA5 (0.41) | MEN1KMT2AHRH3 | |
| SCHEMBL4590339 | 0.84 | HRH3 (0.46) | MEN1KMT2AHRH3 | |
| SCHEMBL4590150 | 0.84 | FGFR1 (0.54) | HRH3 | |
| SCHEMBL4590553 | 0.81 | KCNA5 (0.41) | MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107322-A1 | INDOLE, BENZIMIDAZOLE OR BENZOTRIAZOLE DERIVATIVES INCLUDING A PIPERIDINE OR PIPERAZINE CORE AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |