Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194275 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL3204207 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL3204221 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL3204213 | 0.83 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL5923289 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL4591060 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL5923297 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL3195808 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ATSHRALOX15 | |
| SCHEMBL3200111 | 0.79 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL5923075 | 0.79 | KMT2A (0.49) | SMN1; SMN2MEN1KMT2ATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379249-A4 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1379249-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2002067939-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-09-06 | — | — | WO | claimed |