SCHEMBL45910

SCHEMBL45910

O=C1OC(=O)[C@H]2CCCC[C@H]12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
GMNN O75496 1/20 0.42
PPM1B O75688 1/20 0.42
LMNA P02545 1/20 0.42
PPP1CC P36873 1/20 0.42
TFPI2 P48307 1/20 0.42
RAB9A P51151 1/20 0.42
PPP5C P53041 1/20 0.42
PPP1CA P62136 1/20 0.42
PMP22 Q01453 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TP53 P04637 1/20 0.42
CYP2D6 P10635 1/20 0.42
NFKB1 P19838 1/20 0.42
THPO P40225 1/20 0.42
STS P08842 3/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 1/20 0.38
FNTA P49354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598374 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL15324 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL6237465 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL38660910 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL45891 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL34170 1.00 KDM4E (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL24453322 0.97 KDM4E (0.40) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20963086 0.97 KDM4E (0.40) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL20963058 0.97 KDM4E (0.40) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL16020384 0.97 STS (0.40) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116867942-B Method for preparing lignocellulose and reinforced composite material thereof 浙江大学 2024-12-27 CN claimed
CN-115926397-B Method for preparing degradable nanocellulose reinforced composite material 浙江大学 2024-08-27 CN claimed
CN-115819630-B Method for preparing high-charge nanocellulose 浙江大学衢州研究院 2024-07-05 CN claimed
CN-115504951-B Method for preparing hexahydrophthalide by hydrogenating hexahydrophthalic anhydride 大连理工大学 2024-02-13 CN claimed
CN-116867942-A Method for preparing lignocellulose and reinforced composite material thereof 浙江大学 2023-10-10 CN claimed
CN-112351967-B Process for preparing high purity cis-cyclohexane-1,2-dicarboxylic acid salts 美利肯公司 2023-08-22 CN claimed
CN-116377727-A Laser stealth coating for fabric and application method thereof 西京学院 2023-07-04 CN claimed
CN-114561162-B Integrated electromagnetic induction adhesive tape for laser shock wave binding force detection and preparation method thereof 中国人民解放军空军工程大学 2023-05-26 CN claimed
CN-115926397-A Method for preparing degradable nanocellulose reinforced composite materials 浙江大学 2023-04-07 CN claimed
CN-115819630-A Method for preparing high-charge-capacity nanocellulose 浙江大学衢州研究院 2023-03-21 CN claimed
CN-115707700-A Perospirone hydrochloride isomer impurity and preparation method and application thereof 四川科瑞德制药股份有限公司 2023-02-21 CN claimed
CN-115504951-A Method for preparing hexahydrophthalide by hydrogenation of hexahydrophthalic anhydride 大连理工大学 2022-12-23 CN claimed
CN-114561162-A Integrated electromagnetic induction adhesive tape for detecting laser shock wave binding force and preparation method thereof 中国人民解放军空军工程大学 2022-05-31 CN claimed
CN-114057992-A Resin composition for carbon fiber molding 上纬新材料科技股份有限公司 2022-02-18 CN claimed
US-4465809-A BY REACTING WITH EPOXY COMPOUND THEN CYCLIC ANHYDRIDE, HYDROLYZING; SHEET MOLDING COMPOUNDS PHILLIPS PETROLEUM COMPANY (US) 1984-08-14 US claimed
US-12454530-B2 Amido cyclohexane acid derivatives as LPA receptor inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2025-10-28 US disclosed
US-20250066341-A1 CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-02-27 US disclosed
US-5216018-A Antidyskinetic agents DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-06-01 US disclosed
US-4465808-A GLOSSY PHILLIPS PETROLEUM COMPANY (US) 1984-08-14 US disclosed
US-4465809-A BY REACTING WITH EPOXY COMPOUND THEN CYCLIC ANHYDRIDE, HYDROLYZING; SHEET MOLDING COMPOUNDS PHILLIPS PETROLEUM COMPANY (US) 1984-08-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12454530-B2 Amido cyclohexane acid derivatives as LPA receptor inhibitors LPAR1, LPAR2, LPAR3 KDM4E 3237/4885GMNN 2498/4885PPM1B 1851/4885
US-20250066341-A1 CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS LPAR1, LPAR2, LPAR3 KDM4E 2678/4885GMNN 3878/4885PPM1B 1385/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.