Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45918 | 0.88 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL35112 | 0.87 | NR1H2 (0.65) | NR1H2NR1H3 | |
| SCHEMBL35158 | 0.85 | NR1H2 (0.55) | NR1H2NR1H3 | |
| SCHEMBL35305 | 0.81 | NR1H3 (0.60) | NR1H2NR1H3 | |
| SCHEMBL35291 | 0.78 | NR1H2 (0.64) | NR1H2NR1H3 | |
| SCHEMBL35409 | 0.78 | NR1H2 (0.66) | NR1H2NR1H3 | |
| SCHEMBL35234 | 0.78 | NR1H2 (0.71) | NR1H2NR1H3 | |
| SCHEMBL38954 | 0.78 | NR1H2 (0.70) | NR1H2NR1H3 | |
| SCHEMBL4012188 | 0.77 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL35160 | 0.76 | NR1H2 (0.59) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010205-A1 | NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS | WYETH LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010205-A1 | NOVEL QUINOLINE ESTERS USEFUL FOR TREATING SKIN DISORDERS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.