Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591670 | 0.86 | SSTR5 (0.75) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2958084 | 0.85 | SSTR5 (0.72) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2963831 | 0.84 | SSTR5 (0.73) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL4591321 | 0.83 | SSTR5 (0.74) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2961781 | 0.82 | SSTR5 (0.73) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2957921 | 0.81 | SSTR5 (0.76) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL4592166 | 0.79 | SSTR5 (0.69) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2951619 | 0.79 | SSTR5 (0.75) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2957185 | 0.76 | SSTR5 (0.49) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL2952292 | 0.75 | SSTR5 (0.74) | SSTR5KCNH2SSTR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006128803-A1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2006-12-07 | — | — | WO | disclosed |