Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194277 | 1.00 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL3194285 | 1.00 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL3194270 | 1.00 | MEN1 (0.41) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL3200111 | 0.85 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL3200103 | 0.85 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL3200093 | 0.85 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ATMLMNA | |
| SCHEMBL3189013 | 0.84 | MEN1 (0.42) | MEN1KMT2AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3189002 | 0.84 | MEN1 (0.42) | MEN1KMT2AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3189028 | 0.84 | MEN1 (0.42) | MEN1KMT2AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL3197981 | 0.82 | MEN1 (0.41) | MEN1KMT2ALMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379249-A4 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1379249-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2002067939-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-09-06 | — | — | WO | claimed |