Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.78 |
| ▸ | HTR2A | P28223 | 13/20 | 0.78 |
| ▸ | CHRM1 | P11229 | 10/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4591690 | 0.91 | MCHR1 (0.67) | MCHR1HTR2ACHRM1 | |
| SCHEMBL5426586 | 0.84 | MCHR1 (0.74) | MCHR1HTR2ACHRM1 | |
| SCHEMBL14503852 | 0.80 | MCHR1 (0.81) | MCHR1HTR2ACHRM1 | |
| SCHEMBL4592187 | 0.78 | MCHR1 (1.00) | MCHR1HTR2ACHRM1 | |
| SCHEMBL5461378 | 0.78 | MCHR1 (0.62) | MCHR1HTR2ACHRM1 | |
| SCHEMBL5425531 | 0.77 | MCHR1 (0.68) | MCHR1HTR2ACHRM1 | |
| SCHEMBL4591272 | 0.77 | MCHR1 (0.64) | MCHR1HTR2ACHRM1 | |
| SCHEMBL14505115 | 0.76 | MCHR1 (0.62) | MCHR1HTR2ACHRM1 | |
| SCHEMBL4591565 | 0.75 | MCHR1 (0.80) | MCHR1HTR2ACHRM1 | |
| SCHEMBL5440352 | 0.73 | MCHR1 (0.54) | MCHR1HTR2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943231-A1 | (HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007048802-A1 | (HETERO)ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-03 | — | — | WO | disclosed |