Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3200843 | 1.00 | MEN1 (0.52) | MEN1KMT2AGRM4GRM1SMN1; SMN2 | |
| SCHEMBL3200834 | 1.00 | MEN1 (0.52) | MEN1KMT2AGRM4GRM1SMN1; SMN2 | |
| SCHEMBL3191151 | 0.91 | POLB (0.54) | MEN1KMT2AGRM4GRM1ALDH1A1 | |
| SCHEMBL3191165 | 0.91 | POLB (0.54) | MEN1KMT2AGRM4GRM1ALDH1A1 | |
| SCHEMBL3179075 | 0.85 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3179085 | 0.85 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3181142 | 0.85 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL3181148 | 0.85 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL5922774 | 0.82 | MEN1 (0.52) | MEN1KMT2AGRM4GRM1SMN1; SMN2 | |
| SCHEMBL3187616 | 0.82 | MEN1 (0.52) | MEN1KMT2AGRM4GRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379249-A4 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2008-01-09 | — | — | EP | claimed |
| EP-1379249-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2002067939-A1 | FUSED CYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-09-06 | — | — | WO | claimed |