Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5625331 | 0.73 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL5624965 | 0.73 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL5624693 | 0.72 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL5628511 | 0.72 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL118728 | 0.72 | F10 (0.58) | F10PTGS2 | |
| SCHEMBL28407706 | 0.72 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL28046642 | 0.72 | F10 (0.56) | F10PTGS2 | |
| SCHEMBL5625734 | 0.72 | F10 (0.53) | F10PTGS2 | |
| SCHEMBL28046585 | 0.72 | F10 (0.56) | F10PTGS2 | |
| SCHEMBL5625496 | 0.72 | F10 (0.53) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877404-A2 | NOVEL CYCLIC AMINES | F. Hoffmann-Roche AG (CH) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006114401-A2 | NOVEL CYCLIC AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-11-02 | — | — | WO | disclosed |