⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazine SCHEMBL1226089 | 0.93 | TSHR (0.50) | — | |
| SCHEMBL31437084 | 0.93 | TSHR (0.50) | — | |
| Pyrazine SCHEMBL5179 | 0.93 | — | — | |
| Pyrazine SCHEMBL4020461 | 0.86 | — | — | |
| Pyrazine SCHEMBL10496031 | 0.86 | — | — | |
| Pyrazine SCHEMBL6268124 | 0.86 | — | — | |
| Pyrazine SCHEMBL11336378 | 0.86 | — | — | |
| Pyrazine SCHEMBL940753 | 0.86 | — | — | |
| Pyrazine SCHEMBL8535297 | 0.86 | — | — | |
| Pyrazine SCHEMBL2682548 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080032913-A1 | Masking of mineral oil odor and fragrancing of mineral oils | SYMRISE GMBH & CO. KG (DE) | 2008-02-07 | — | — | US | claimed |
| EP-1884555-A2 | Masking mineral oil smell and scenting of mineral oils | Symrise GmbH & Co. KG (DE) | 2008-02-06 | — | — | EP | claimed |
| CN-114805389-A | Tricyclic dihydroimidazopyrimidinone derivatives, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-112778331-B | Tricyclic dihydroimidazopyrimidinone derivatives, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-112778331-A | Tricyclic dihydroimidazopyrimidinone derivatives, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-109983091-A | Powdered thermosetting compositions for coatings with lower no dusting temperature | 帝斯曼知识产权资产管理有限公司 | 2019-07-05 | — | — | CN | disclosed |
| CN-106459655-B | 2K powdered thermosetting compositions for coatings | 帝斯曼知识产权资产管理有限公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-105765001-B | Thermosetting powder coating compositions comprising methyl-substituted benzoyl peroxide | 帝斯曼知识产权资产管理有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-106459655-A | 2k thermosetting powder coating compositions | 帝斯曼知识产权资产管理有限公司 | 2017-02-22 | — | — | CN | disclosed |