Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 11/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794752 | 0.92 | MEN1 (0.47) | ALDH1A1GAAMEN1KMT2AEGFR | |
| SCHEMBL3799137 | 0.91 | NPC1 (0.54) | MEN1KMT2AEGFRNPC1RAB9A | |
| SCHEMBL3794854 | 0.91 | MEN1 (0.48) | MEN1KMT2AEGFRNPC1RAB9A | |
| SCHEMBL3796447 | 0.85 | MKNK2 (0.54) | MEN1KMT2AEGFRRAB9AMKNK1 | |
| SCHEMBL4594135 | 0.83 | MKNK2 (0.47) | GAAEGFRMAPTMKNK1MKNK2 | |
| SCHEMBL3798528 | 0.83 | MEN1 (0.49) | MEN1KMT2AEGFRNPC1RAB9A | |
| SCHEMBL3794289 | 0.83 | MEN1 (0.49) | MEN1KMT2AEGFRNPC1RAB9A | |
| SCHEMBL3794275 | 0.82 | EGFR (0.48) | EGFRERBB2KCNH2 | |
| SCHEMBL13434909 | 0.81 | MKNK1 (0.42) | EGFRERBB2KCNH2PDE4APDE4B | |
| SCHEMBL3795348 | 0.81 | MEN1 (0.48) | MEN1KMT2AEGFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899353-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DeveloGen Aktiengesellschaft (DE) | 2008-03-19 | — | — | EP | claimed |
| WO-2006136402-A1 | THIENOPYRIMIDINES FOR PHARMACEUTICAL COMPOSITIONS | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2006-12-28 | — | — | WO | claimed |