Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27690676 | 0.98 | KDM4E (0.46) | KDM4EGAAALDH1A1GLALMNA | |
| SCHEMBL334854 | 0.85 | CA12 (0.47) | KDM4EGAAALDH1A1GLALMNA | |
| SCHEMBL115719 | 0.85 | KDM4C (0.53) | KDM4EGAAALDH1A1GLAHTT | |
| SCHEMBL30578227 | 0.85 | KDM4C (0.53) | KDM4EGAAALDH1A1GLAHTT | |
| SCHEMBL22731931 | 0.84 | GPBAR1 (0.43) | KDM4EGAAALDH1A1GLALMNA | |
| Hydrochloric Acid SCHEMBL459608 | 0.83 | KDM4C (0.52) | KDM4EGAAALDH1A1GLAHTT | |
| SCHEMBL607011 | 0.83 | MKNK1 (0.57) | KDM4EGAAALDH1A1GLAHTT | |
| SCHEMBL1554575 | 0.83 | KDM4E (0.64) | KDM4EGAAALDH1A1GLALMNA | |
| SCHEMBL22731923 | 0.82 | IKBKB (0.45) | KDM4EGAAALDH1A1GLALMNA | |
| SCHEMBL1797967 | 0.81 | KDM4E (0.41) | KDM4EGAAALDH1A1GLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85105898-A | With the manufacture method that is 2-benzyl-4-(4-pyridine radicals) thiazoles He its derivative of immunomodulator | — | 1987-01-21 | — | — | CN | claimed |
| US-20230234945-A1 | AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-27 | — | — | US | disclosed |
| WO-2015187934-A1 | FUNCTIONALIZED HETROARYL ENONES EXHIBITING NRF2 ACTIVATION AND THEIR METHOD OF USE | CUREVEDA, LLC (US) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015187934-A1 | FUNCTIONALIZED HETROARYL ENONES EXHIBITING NRF2 ACTIVATION AND THEIR METHOD OF USE | CUREVEDA, LLC (US) | 2015-12-10 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| US-4725606-A | AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4697012-A | IMMUNOLOGY, ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1987-09-29 | — | — | US | disclosed |
| CN-85105898-A | With the manufacture method that is 2-benzyl-4-(4-pyridine radicals) thiazoles He its derivative of immunomodulator | — | 1987-01-21 | — | — | CN | disclosed |
| EP-0169502-A2 | 2-Benzyl-4-(2-morpholino)-4-Pyriol) Thiazole | MERCK & CO. INC. (US) | 1986-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234945-A1 | AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES | CYP1B1, DDT, CYP1A1 | KDM4E 542/4885GAA 805/4885ALDH1A1 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.