Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.51 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KIF5B | P33176 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27988358 | 0.98 | EGFR (0.50) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| Formaldehyde SCHEMBL28199969 | 0.94 | EGFR (0.46) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| SCHEMBL4728705 | 0.93 | EGFR (0.51) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| Hydrochloric Acid SCHEMBL28202312 | 0.92 | EGFR (0.50) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| SCHEMBL241727 | 0.85 | EGFR (0.58) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| Hydrochloric Acid SCHEMBL8814048 | 0.84 | EGFR (0.56) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| SCHEMBL28703821 | 0.82 | EGFR (0.44) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| Formaldehyde SCHEMBL28061098 | 0.81 | EGFR (0.53) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| SCHEMBL6030966 | 0.79 | EGFR (0.46) | EGFRFGFR4PDGFRBPDGFRAKDM4E | |
| SCHEMBL30267593 | 0.79 | EGFR (0.51) | EGFRFGFR4PDGFRBPDGFRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264889-B | Method suitable for industrial production and preparation of gefitinib | 广西师范大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-113200966-B | Furosetinib derivative, pharmaceutical composition and application | 深圳大学 | 2022-07-22 | — | — | CN | disclosed |
| EP-1904458-A1 | METHOD FOR THE PRODUCTION OF QUINAZOLINONE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007003486-A1 | METHOD FOR THE PRODUCTION OF QUINAZOLINONE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-11 | — | — | WO | disclosed |