Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.93 |
| ▸ | HTT | P42858 | 1/20 | 0.93 |
| ▸ | GAA | P10253 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061430 | 0.96 | MAPT (1.00) | MAPTHTTGAALMNARAB9A | |
| Hydrochloric Acid SCHEMBL27689202 | 0.94 | MAPT (0.96) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL27671467 | 0.89 | MAPT (0.86) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL1471759 | 0.88 | MAPT (0.77) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL13389060 | 0.88 | MAPT (0.77) | MAPTHTTGAALMNARAB9A | |
| Trifluoroacetic Acid SCHEMBL27735880 | 0.86 | MAPT (0.81) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL11705109 | 0.86 | TRPV1 (0.82) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL12915848 | 0.86 | MAPT (0.80) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL13356363 | 0.86 | MAPT (0.80) | MAPTHTTGAALMNARAB9A | |
| SCHEMBL8012743 | 0.85 | TRPV1 (0.81) | MAPTHTTGAALMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1898910-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007000436-A1 | QUINOLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-01-04 | — | — | WO | disclosed |