Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356575 | 0.97 | DPP8 (0.48) | DPP8DPP9DPP4BACE1CTSD | |
| SCHEMBL29777885 | 0.94 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1CTSD | |
| SCHEMBL30734094 | 0.94 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1CTSD | |
| SCHEMBL29373300 | 0.93 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1FOLH1 | |
| SCHEMBL31376476 | 0.93 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1FOLH1 | |
| SCHEMBL31376469 | 0.93 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1FOLH1 | |
| SCHEMBL29518787 | 0.93 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1FOLH1 | |
| SCHEMBL31376475 | 0.93 | FOLH1 (0.48) | DPP8DPP9DPP4BACE1FOLH1 | |
| SCHEMBL11697730 | 0.92 | NMT1 (0.48) | DPP8DPP9DPP4BACE1CTSD | |
| SCHEMBL30358359 | 0.91 | FOLH1 (0.50) | DPP8DPP9DPP4BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1913154-A2 | METHODS FOR THE SCREENING OF ANTIBACTERIAL SUBSTANCES | INSERM (Institut National de la Santé et de la Recherche Medicale) (FR) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007014951-A2 | METHODS FOR THE SCREENING OF ANTIBACTERIAL SUBSTANCES | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2007-02-08 | — | — | WO | disclosed |