SCHEMBL459388

SCHEMBL459388

CCC(=O)N(S)CC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.43
TDP1 Q9NUW8 4/20 0.36
EYA2 O00167 1/20 0.36
APP P05067 1/20 0.36
ACE P12821 1/20 0.36
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
ADRA2A P08913 1/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
DRD1 P21728 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
CYP2C19 P33261 1/20 0.35
ADRA1A P35348 1/20 0.35
DRD3 P35462 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8219027 0.98 FFAR3 (0.41) FFAR3TDP1EYA2APPACE
SCHEMBL11231593 0.76 FFAR3 (0.37) FFAR3KDM4EALOX15HDAC3HDAC1
SCHEMBL18193503 0.76
Water SCHEMBL11219174 0.75 FFAR3 (0.36) FFAR3KDM4EALOX15HDAC3HDAC1
SCHEMBL6444629 0.74 FFAR3 (0.47) FFAR3TDP1EYA2APPACE
SCHEMBL5595896 0.72 FFAR3 (0.45) FFAR3TDP1EYA2APPACE
SCHEMBL8602002 0.72 FFAR3 (0.45) FFAR3TDP1EYA2APPACE
SCHEMBL27924625 0.70
Hydrochloric Acid SCHEMBL11310560 0.70 FFAR3 (0.43) FFAR3TDP1EYA2APPACE
SCHEMBL27889732 0.70 FFAR3 (0.43) FFAR3TDP1EYA2APPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 595 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118576786-A Multifunctional hydrophilic lubricating coating and preparation method thereof 四川大学华西医院 2024-09-03 CN claimed
CN-116272705-B Preparation method and application of core-shelled nanocluster hydrogel microsphere 广东工业大学 2023-09-19 CN claimed
CN-116686923-A Sea buckthorn stachyose beverage and production process thereof 杭州懿满天下健康管理有限公司 2023-09-05 CN claimed
CN-115626808-B Environment-friendly high-strength modified phosphogypsum regenerated lightweight aggregate and preparation method and application thereof 湖北聚海环境科技有限公司 2023-08-11 CN claimed
CN-116272705-A Preparation method and application of core-shelled nanocluster hydrogel microsphere 广东工业大学 2023-06-23 CN claimed
CN-115626808-A Environment-friendly high-strength modified phosphogypsum regenerated light aggregate and preparation method and application thereof 湖北聚海环境科技有限公司 2023-01-20 CN claimed
EP-2219619-B1 DISULFIDE CHEMOTHERAPEUTIC AGENTS AND METHODS OF USE THEREOF LANKENAU INST MEDICAL RES (US) 2020-07-15 EP claimed
US-20200131563-A1 CONTROL NUCLEIC ACIDS, AND COMPOSITIONS, KITS, AND USES THEREOF Life Technologies Corporation 2020-04-30 US claimed
CN-107793563-B A kind of polyethylene glycol omega-amino acid maleimide derivatives and preparation method thereof 湖南华腾制药有限公司 2019-09-20 CN claimed
CN-107486169-B A kind of preparation method of mercapto-propionyl-glycin modified magnetic complex microsphere 济南大学 2019-03-15 CN claimed
CN-1183720-A Method for treating macular degeneration J E REPINE (US) 1998-06-03 CN claimed
EP-0819003-A1 A METHOD FOR THE TREATMENT OF MACULAR DEGENERATION REPINE, John E. (US) 1998-01-21 EP claimed
US-5596011-A Method for the treatment of macular degeneration JACOBS, MICHAEL S. AND SHEILA GALYNN JACOBS 1997-01-21 US claimed
WO-1996031212-A1 A METHOD FOR THE TREATMENT OF MACULAR DEGENERATION REPINE JOHN E (US) 1996-10-10 WO claimed
EP-0318773-B1 PHARMACEUTICAL PREPARATION FOR CHOLELITHOLYSIS Leuschner, Ulrich, Prof. Dr. (DE) 1991-10-16 EP claimed
EP-0274106-A2 N-(trans-p-hydroxy-cyclohexyl)-(2-amino-3,5-dibromo)benzylamine salts possessing mucolytic activity ERREGIERRE INDUSTRIA CHIMICA Spa (IT) 1988-07-13 EP claimed
EP-0096013-B1 SALTS OF ERYTHROMYCIN SHOWING A COMBINED THERAPEUTIC ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM NUOVO CONSORZIO SANITARIO NAZIONALE (IT) 1986-07-23 EP claimed
EP-0015544-B1 DERIVATIVES OF THE MERCAPTOPROPIONAMIDO-ACETIC ACID, PROCESS FOR THE PREPARATION THEREOF AND COMPOSITIONS ZAMBON S.p.A. (IT) 1983-01-05 EP claimed
US-4346234-A Process for the preparation of the sodium salt of mercaptopropionylglycine GARGANI PIETRO 1982-08-24 US claimed
EP-0015544-A2 Derivatives of the mercaptopropionamido-acetic acid, process for the preparation thereof and compositions ZAMBON S.p.A. (IT) 1980-09-17 EP claimed