Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.64 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.64 |
| ▸ | PREP | P48147 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL665335 | 1.00 | DPP4 (0.64) | DPP4DPP7DPP8PREP | |
| SCHEMBL5658833 | 0.91 | DPP4 (0.69) | DPP4DPP7DPP8PREP | |
| SCHEMBL663681 | 0.91 | DPP4 (0.69) | DPP4DPP7DPP8PREP | |
| SCHEMBL664898 | 0.88 | DPP4 (0.67) | DPP4DPP7DPP8PREP | |
| SCHEMBL5659759 | 0.88 | DPP4 (0.67) | DPP4DPP7DPP8PREP | |
| SCHEMBL1436023 | 0.87 | DPP4 (0.75) | DPP4DPP7DPP8 | |
| SCHEMBL665455 | 0.87 | DPP4 (0.75) | DPP4DPP7DPP8 | |
| SCHEMBL6828187 | 0.87 | PREP (0.51) | DPP4DPP7DPP8PREP | |
| SCHEMBL666219 | 0.87 | DPP4 (0.74) | DPP4DPP7DPP8 | |
| SCHEMBL4594039 | 0.87 | DPP4 (0.74) | DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259925-A1 | DPP IV INHIBITORS | BOEHRINGER MARKUS | 2007-11-08 | — | — | US | claimed |
| EP-1917001-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| US-20070259925-A1 | DPP IV INHIBITORS | BOEHRINGER MARKUS | 2007-11-08 | — | — | US | disclosed |
| WO-2007017423-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259925-A1 | DPP IV INHIBITORS | DPP4, DPP3, DPP7 | DPP4 1/4885DPP7 3/4885DPP8 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.