Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594484 | 0.95 | TLR7 (0.47) | TLR8TLR7NUDT1 | |
| SCHEMBL4319396 | 0.85 | TLR7 (0.51) | TLR8TLR7 | |
| SCHEMBL1490872 | 0.83 | TLR7 (0.49) | TLR8TLR7NUDT1 | |
| SCHEMBL4080325 | 0.83 | TLR8 (0.54) | TLR8TLR7NUDT1 | |
| SCHEMBL1490891 | 0.82 | TLR8 (0.59) | TLR8TLR7NUDT1 | |
| SCHEMBL1490683 | 0.81 | TLR7 (0.61) | TLR8TLR7NUDT1 | |
| SCHEMBL3867540 | 0.81 | TLR7 (0.51) | TLR8TLR7NUDT1 | |
| SCHEMBL1490813 | 0.81 | TLR7 (0.60) | TLR8TLR7NUDT1 | |
| SCHEMBL3872419 | 0.80 | TLR7 (0.52) | TLR8TLR7NUDT1 | |
| SCHEMBL1490657 | 0.80 | TLR7 (0.47) | TLR8TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685129-A4 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1685129-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M Innovative Properties Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005048933-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |