Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 4/20 | 0.53 |
| ▸ | PIM1 | P11309 | 13/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 8/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.45 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4330143 | 0.82 | FYN (0.57) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL4333814 | 0.82 | RET (0.59) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL4594307 | 0.81 | PIM1 (0.70) | SCN5APIM1PIM2KCNH2 | |
| SCHEMBL4342860 | 0.80 | FYN (0.58) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL4558598 | 0.80 | FYN (0.78) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL102242 | 0.80 | PIM1 (0.51) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL4330269 | 0.78 | FYN (0.56) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL4339484 | 0.78 | RET (0.70) | PIM1PIM2KCNH2FYN | |
| SCHEMBL4595169 | 0.78 | FYN (0.67) | SCN5APIM1PIM2FLT3KCNH2 | |
| SCHEMBL4595261 | 0.78 | PIK3CG (0.60) | SCN5APIM1PIM2FLT3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1873157-A1 | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-01-02 | — | — | EP | disclosed |