Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | TACR1 | P25103 | 4/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GCG | P01275 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GIPR | P48546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4594753 | 0.89 | MAPT (0.37) | SSTR1SSTR5MEN1KMT2AMAPT | |
| SCHEMBL4593639 | 0.89 | SSTR5 (0.39) | SSTR1SSTR5MEN1KMT2ATACR1 | |
| SCHEMBL4594236 | 0.84 | SSTR5 (0.37) | SSTR1SSTR5TACR1KDR | |
| SCHEMBL4593460 | 0.83 | SSTR5 (0.47) | SSTR1SSTR5MAPTTACR1KDR | |
| SCHEMBL4594219 | 0.83 | SSTR5 (0.36) | SSTR1SSTR5MAPTL3MBTL1TACR1 | |
| SCHEMBL4593292 | 0.83 | SSTR5 (0.39) | SSTR1SSTR5KDR | |
| SCHEMBL4593872 | 0.82 | SSTR5 (0.54) | SSTR1SSTR5MAPTL3MBTL1TACR1 | |
| SCHEMBL4594382 | 0.82 | SSTR5 (0.40) | SSTR1SSTR5MAPTTACR1ALDH1A1 | |
| SCHEMBL4593537 | 0.82 | SSTR5 (0.40) | SSTR1SSTR5TACR1KDR | |
| SCHEMBL4594820 | 0.82 | SSTR5 (0.39) | SSTR5L3MBTL1TACR1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |