Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL2140500 | 1.00 | TSHR (0.44) | TSHRALDH1A1FFAR3HDAC1HDAC2 | |
| Butane SCHEMBL7258069 | 1.00 | — | — | |
| Butane SCHEMBL17460145 | 0.86 | TSHR (0.44) | TSHRALDH1A1FFAR3HDAC1HDAC2 | |
| Butane SCHEMBL22813 | 0.86 | — | — | |
| Butane SCHEMBL1734106 | 0.84 | — | — | |
| Butane SCHEMBL8628663 | 0.84 | TSHR (0.50) | TSHRALDH1A1LMNATHRBCES2 | |
| Butane SCHEMBL2470336 | 0.84 | TSHR (0.50) | TSHRALDH1A1LMNATHRBCES2 | |
| Butane SCHEMBL9292387 | 0.84 | TSHR (0.50) | TSHRALDH1A1LMNATHRBCES2 | |
| Butane SCHEMBL3593 | 0.84 | — | — | |
| Butane SCHEMBL21633593 | 0.84 | FFAR3 (0.54) | TSHRALDH1A1FFAR3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014047117-A1 | PROCESS FOR PREPARING PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-03-27 | — | — | WO | disclosed |
| US-20080249242-A1 | Aqueous Vinyl Graft Copolymer Compositions | DSM IP ASSETS B.V. (NL) | 2008-10-09 | — | — | US | disclosed |
| EP-1928926-A1 | AQUEOUS VINYL GRAFT COPOLYMER COMPOSITIONS | DSMIP Assets B.V. (NL) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007039051-A1 | AQUEOUS VINYL GRAFT COPOLYMER COMPOSITIONS | DSM IP ASSETS B.V. (NL) | 2007-04-12 | — | — | WO | disclosed |
| EP-1598400-A2 | Wear-resistant coating composition and method of producing A coating | Rohm and Haas Company (US) | 2005-11-23 | — | — | EP | disclosed |
| EP-1162237-B1 | Method of producing a wear-resistant coating | ROHM & HAAS (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-0832949-B1 | Coating composition having extended storage stability | ROHM & HAAS (US) | 2004-06-23 | — | — | EP | disclosed |
| US-6566437-B2 | Polycarbodiimide, aqueous emulsion polymer reactive with the carbodiimide groups and an alkoxysilane, and the alkoxysilane has a group reactive with the emulsion polymer; traffic marking compositions | ROHM AND HAAS COMPANY | 2003-05-20 | — | — | US | disclosed |
| US-20020007001-A1 | Wear-resistant coating composition and method of producing a coating | ROHM AND HAAS COMPANY | 2002-01-17 | — | — | US | disclosed |
| EP-1162237-A1 | Wear-resistant coating composition and method of producing a coating | ROHM AND HAAS COMPANY (US) | 2001-12-12 | — | — | EP | disclosed |
| US-5939514-A | ANIONICALLY STABILIZED BINDER POLYMER HAVING AT LEAST ONE REACTIVE FUNCTIONAL PENDENT MOIETY, OR A BLEND OF THE BINDER POLYMER AND A POLYFUNCTIONAL AMINE; QUICK-DRYING ROAD MARKING PAINTS CAN BE APPLIED WITH CONVENTIONAL STRIPING EQUIPMENT | ROHM AND HAAS COMPANY (US) | 1999-08-17 | — | — | US | disclosed |
| EP-0832949-A2 | Coating composition having extended storage stability | ROHM AND HAAS COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0754663-B1 | Method for producing efflorescence resistant coating on cementitious substrate | ROHM & HAAS (US) | 1998-03-04 | — | — | EP | disclosed |
| US-5718943-A | FOAMING AN AQUEOUS EVAPORABLE CARRIER CONTAINING A LATEX BINDER AND FOAMING AGENT; APPLYING; COLLAPSING | ROHM AND HAAS COMPANY (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0754663-A1 | Method for producing efflorescence resistant coating on cementitious substrate | ROHM AND HAAS COMPANY (US) | 1997-01-22 | — | — | EP | disclosed |
| US-4343728-A | POLYMERIZED IN HIGH BOILING ALCOHOL | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1982-08-10 | — | — | US | disclosed |