Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.49 |
| ▸ | PREP | P48147 | 5/20 | 0.44 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830438 | 1.00 | DPP4 (0.49) | DPP4PREPGRM5DPP7 | |
| SCHEMBL4594040 | 0.89 | DPP4 (0.46) | DPP4PREPDPP7 | |
| SCHEMBL6828165 | 0.87 | PREP (0.47) | DPP4PREPDPP7 | |
| SCHEMBL4594327 | 0.87 | PREP (0.47) | DPP4PREPDPP7 | |
| SCHEMBL4594042 | 0.85 | PREP (0.42) | DPP4PREPDPP7 | |
| SCHEMBL6830053 | 0.85 | PREP (0.42) | DPP4PREPDPP7 | |
| SCHEMBL664182 | 0.82 | DPP4 (0.59) | DPP4PREPDPP7 | |
| SCHEMBL6828008 | 0.78 | DPP4 (0.45) | DPP4PREPDPP7 | |
| SCHEMBL6828026 | 0.77 | DPP4 (0.47) | DPP4PREPDPP7 | |
| SCHEMBL4594463 | 0.77 | DPP4 (0.47) | DPP4PREPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917001-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007017423-A2 | PHARMACEUTICAL COMPOSITION COMPRISING A DPP-IV INHIBITOR | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-15 | — | — | WO | disclosed |