Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.41 |
| ▸ | DRD2 | P14416 | 9/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077178 | 0.83 | DRD3 (0.41) | DRD3KCNH2DRD2CYP1A2MAOA | |
| SCHEMBL378650 | 0.81 | DRD3 (0.40) | DRD3KCNH2DRD2CYP1A2MGLL | |
| SCHEMBL378642 | 0.79 | DRD3 (0.40) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL6003466 | 0.78 | DRD3 (0.51) | DRD3KCNH2DRD2CYP1A2 | |
| Hexane SCHEMBL378364 | 0.77 | DRD3 (0.39) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL4551340 | 0.76 | DRD3 (0.46) | DRD3KCNH2DRD2MAOAMAOB | |
| SCHEMBL6003627 | 0.76 | DRD3 (0.46) | DRD3KCNH2DRD2MAOAMAOB | |
| SCHEMBL6003488 | 0.76 | DRD3 (0.46) | DRD3KCNH2DRD2MAOAMAOB | |
| SCHEMBL6003533 | 0.75 | DRD3 (0.54) | DRD3KCNH2DRD2CYP1A2 | |
| SCHEMBL10107827 | 0.73 | DRD3 (0.57) | DRD3KCNH2DRD2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871768-A1 | AZABICYCLO (3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006136223-A1 | AZABICYCLO (3.1.0) HEXANE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |