Thioglycolic Acid

Thioglycolic Acid

SCHEMBL4595079

CCC.O=C(O)CS.O=C(O)CS.O=C(O)CS

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.53
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
TSHR P16473 5/20 0.40
HSD17B10 Q99714 2/20 0.40
AKR1B1 P15121 1/20 0.38
FOLH1 Q04609 1/20 0.38
KMT2A Q03164 2/20 0.38
LDHA P00338 1/20 0.38
SRR Q9GZT4 1/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.38
ALKBH5 Q6P6C2 1/20 0.38
SUCNR1 Q9BXA5 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
GPR84 Q9NQS5 6/20 0.36
PPARG P37231 6/20 0.36
PPARD Q03181 6/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thioglycolic Acid SCHEMBL16795985 1.00 FFAR3 (0.53) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL10607018 1.00
Thioglycolic Acid SCHEMBL11854674 0.92
Thioglycolic Acid SCHEMBL3284619 0.89
Propionic Acid SCHEMBL27327849 0.89 FFAR3 (0.71) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL476547 0.89 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL27303874 0.89 FFAR3 (0.71) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL30789757 0.89 FFAR3 (0.50) FFAR3HDAC3HDAC1HDAC2HDAC8
Thioglycolic Acid SCHEMBL28339906 0.89
Thioglycolic Acid SCHEMBL3079958 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1885763-B1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG IND OHIO INC (US) 2017-07-12 EP disclosed
EP-1885763-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG Industries Ohio, Inc. (US) 2008-02-13 EP disclosed
EP-1877839-A2 THERMOSETTING POLY(THIO)URETHANE FORMULATION COMPRISING AT LEAST ONE BLOCK COPOLYMER AND USE THEREOF IN OPTICS FOR THE PRODUCTION OF ORGANIC LENSES HAVING IMPROVED TOUGHNESS ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) 2008-01-16 EP disclosed
WO-2006130339-A1 HIGH IMPACT POLY(URETHANE UREA) POLYSULFIDES PPG INDUSTRIES OHIO, INC. (US) 2006-12-07 WO disclosed
WO-2006103371-A2 THERMOSETTING POLY(THIO)URETHANE FORMULATION COMPRISING AT LEAST ONE BLOCK COPOLYMER AND USE THEREOF IN OPTICS FOR THE PRODUCTION OF ORGANIC LENSES HAVING IMPROVED TOUGHNESS ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2006-10-05 WO disclosed
US-20050282991-A1 High impact poly (urethane urea) polysulfides PPG INDUSTRIES OHIO, INC. 2005-12-22 US disclosed
US-5019483-A Aqueous developable photoresist containing weak alkali soluble or dispersible thiol compounds 501 INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1991-05-28 US disclosed