SCHEMBL4595320

SCHEMBL4595320

N=C(N)NCCC[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.54
NPY4R P50391 11/20 0.47
NPY1R P25929 6/20 0.47
NPY2R P49146 4/20 0.47
NPY5R Q15761 4/20 0.47
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
NOD1 Q9Y239 2/20 0.40
SIRT5 Q9NXA8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31171160 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL29902836 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL27613292 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL30414248 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL30045741 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL31420018 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL31452998 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL30423428 1.00 FOLH1 (0.54) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL30412991 0.97 FOLH1 (0.51) FOLH1NPY4RNPY1RNPY2RNPY5R
SCHEMBL29874727 0.97 FOLH1 (0.52) FOLH1NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0502007-A4 METHOD FOR REDUCING BLOOD CHOLESTEROL USING ARGININE 1992-11-19 EP claimed
US-5157022-A Administering arginine nicotinate and di- and tripeptides of arginine BARBUL ADRIAN (US) 1992-10-20 US claimed
EP-0502007-A1 ARGININE NICOTINATE FOR REDUCING BLOOD CHOLESTEROL BARBUL, Adrian (US) 1992-09-09 EP claimed
WO-1991007188-A1 METHOD FOR REDUCING BLOOD CHOLESTEROL USING ARGININE BARBUL ADRIAN (US) 1991-05-30 WO claimed
EP-4731002-A2 SYSTEMS FOR PRODUCTION OF PRODUCTS TO PROMOTE NITROGEN USE EFFICIENCY IN PLANTS Tenfold Technologies, LLC (US) 2026-04-29 EP disclosed
WO-2024263793-A2 SYSTEMS FOR PRODUCTION OF PRODUCTS TO PROMOTE NITROGEN USE EFFICIENCY IN PLANTS Tenfold Technologies, LLC (US) 2024-12-26 WO disclosed
US-20080145424-A1 Sustained release L-arginine formulations and methods of manufacture and use ENOS PHRAMACEUTICALS, INC. (US) 2008-06-19 US disclosed
CN-101184510-A Methods of treating various disorders by administering sustained release L-arginine ENOS PHARMACEUTICALS INC (US) 2008-05-21 CN disclosed
EP-1846037-A4 METHODS OF TREATING VARIOUS CONDITIONS BY ADMINISTRATION OF SUSTAINED RELEASE L-ARGININE PALMETTO PHARMACEUTICALS LLC (US) 2008-03-12 EP disclosed
EP-1874277-A1 SUSTAINED RELEASE L-ARGININE FORMULATIONS AND METHODS OF MANUFACTURE AND USE Palmetto Pharmaceuticals, LLC (US) 2008-01-09 EP disclosed
EP-1846037-A1 METHODS OF TREATING VARIOUS CONDITIONS BY ADMINISTRATION OF SUSTAINED RELEASE L-ARGININE Enos Pharmaceuticals, Inc. (US) 2007-10-24 EP disclosed
US-20070219208-A1 Methods for Treating Cancer NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-09-20 US disclosed
US-20060029668-A1 Sustained release L-arginine formulations and methods of manufacture and use ENOS PHARMACEUTICALS, INC. 2006-02-09 US disclosed
CN-1731985-A Sustained release L-arginine formulations and methods of production and use thereof ENOS PHARMACEUTICALS INC (US) 2006-02-08 CN disclosed
US-20050288372-A1 Methods of treating various conditions by administration of sustained released L-Arginine ENOS PHARMACEUTICALS, INC. (US) 2005-12-29 US disclosed
US-20050287210-A1 Sustained release L-arginine formulations and methods of manufacture and use ENOS PHARMACEUTICALS, INC. (US) 2005-12-29 US disclosed
US-20050288373-A1 Methods of treating various conditions by administration of sustained release L-arginine PALMETTO PHARMACEUTICALS, LLC (GE) 2005-12-29 US disclosed
WO-2003094909-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF INTERMITTENT CLAUDICATION OR ALZHEIMER'S DISEASE ENOS PHARMACEUTICALS, INC. (US) 2003-11-20 WO disclosed
US-6475530-B1 Methods and compositions for producing weight loss HSBC BANK CANADA (CA) 2002-11-05 US disclosed
US-5157022-A Administering arginine nicotinate and di- and tripeptides of arginine BARBUL ADRIAN (US) 1992-10-20 US disclosed