⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451017 | 0.81 | — | — | |
| SCHEMBL5352357 | 0.75 | — | — | |
| SCHEMBL5344475 | 0.73 | DPP4 (0.33) | — | |
| SCHEMBL1112 | 0.70 | — | — | |
| SCHEMBL10538268 | 0.69 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL682268 | 0.69 | — | — | |
| SCHEMBL18677545 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3518668 | 0.67 | — | — | |
| SCHEMBL4407815 | 0.67 | CA1 (0.32) | — | |
| SCHEMBL15906755 | 0.67 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979953-A | Method for preparing saflufenacil intermediate | 帕潘纳(北京)科技有限公司 | 2022-01-28 | — | — | CN | claimed |
| US-10398677-B2 | N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B | JANSSEN SCIENCES IRELAND UC (IE) | 2019-09-03 | — | — | US | claimed |
| US-20180153857-A1 | N-PHENYL-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UC (IE) | 2018-06-07 | — | — | US | claimed |
| CN-118772022-A | Preparation method of N-methyl-N-isopropyl amino sulfonamide | 帕潘纳(北京)科技有限公司 | 2024-10-15 | — | — | CN | disclosed |
| WO-2024201460-A1 | PROCESS FOR THE PREPARATION OF SULFAMIDE DERIVATIVES | ADAMA AGAN LTD. (IL) | 2024-10-03 | — | — | WO | disclosed |
| CN-117956992-A | MENIN-MLL interaction inhibitors | 赛达克斯制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-113979953-A | Method for preparing saflufenacil intermediate | 帕潘纳(北京)科技有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-10398677-B2 | N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B | JANSSEN SCIENCES IRELAND UC (IE) | 2019-09-03 | — | — | US | disclosed |
| US-10398677-B2 | N-phenyl-carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis B | JANSSEN SCIENCES IRELAND UC (IE) | 2019-09-03 | — | — | US | disclosed |
| US-20180153857-A1 | N-PHENYL-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UC (IE) | 2018-06-07 | — | — | US | disclosed |
| US-9920002-B2 | Methods for producing sulfonic acid diamides | BASF SE (DE) | 2018-03-20 | — | — | US | disclosed |
| US-6939867-B2 | Phenyl sulfamide derivatives as dietetics, antidiabetics, and hypotensive agents | PFIZER INC. (US) | 2005-09-06 | — | — | US | disclosed |
| US-20050159622-A1 | Method for the production of sulphamic acid halogenides | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-21 | — | — | US | disclosed |
| EP-1230224-B1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2004-12-29 | — | — | EP | disclosed |
| US-6821980-B1 | Substituted 5-benzyl-2,4-diaminopyrimidines | BASILEA PHARMACEUTICA AG (CH) | 2004-11-23 | — | — | US | disclosed |
| US-20020128247-A1 | Beta3 agonists and uses thereof | DOW ROBERT L (US) | 2002-09-12 | — | — | US | disclosed |
| EP-1236723-A1 | Sulfamide derivatives useful as beta3 agonists and pharmaceutical uses thereof | Pfizer Products Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| EP-1230224-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032633-A1 | SUBSTITUTED 5-BENZYL-2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2001-05-10 | — | — | WO | disclosed |
| WO-2000018770-A1 | PYRROLOPYRROLONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXO GROUP LIMITED (GB) | 2000-04-06 | — | — | WO | disclosed |