SCHEMBL4596983

SCHEMBL4596983

NC(CO)c1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5761112 1.00
SCHEMBL28682937 0.81 KMT2A (0.40)
SCHEMBL5810409 0.79
SCHEMBL12261901 0.77
SCHEMBL12261820 0.77
Hydrochloric Acid SCHEMBL28933988 0.77 CYP2C19 (0.38)
SCHEMBL12261798 0.77
SCHEMBL29118390 0.77 KMT2A (0.42)
SCHEMBL5676909 0.77 CYP2C9 (0.36)
SCHEMBL23163319 0.76 MIF (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435840-A2 Process for the preparation of 2-(2-furyl) ethanol amine MONSANTO COMPANY (US) 1991-07-03 EP claimed
US-4962212-A Process for the preparation of 2-(2-furyl)ethanol amine MONSANTO COMPANY (US) 1990-10-09 US claimed
JP-3197476-A None JP disclosed
JP-3197476-A None JP disclosed
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2025-11-06 US disclosed
EP-4504739-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2025-02-12 EP disclosed
WO-2023196429-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-12 WO disclosed
EP-1907353-A2 BIS-AROMATIC AMIDES AND THEIR USES AS SWEET FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS Senomyx Inc. (US) 2008-04-09 EP disclosed
WO-2006138512-A2 BIS-AROMATIC AMIDES AND THEIR USES AS SWEET FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS SENOMYX, INC. (US) 2006-12-28 WO disclosed
EP-1458719-A1 PYRIDOQUINOXALINE ANTIVIRALS PHARMACIA &amp; UPJOHN COMPANY (US) 2004-09-22 EP disclosed
WO-2003053971-A1 PYRIDOQUINOXALINE ANTIVIRALS PHARMACIA & UPJOHN COMPANY (US) 2003-07-03 WO disclosed
JP-H03197476-A PREPARATION OF 2-(2-FURYL)ETHANOL AMINE MONSANTO CO 1991-08-28 JP disclosed
JP-H03197476-A PREPARATION OF 2-(2-FURYL)ETHANOL AMINE MONSANTO CO 1991-08-28 JP disclosed
EP-0435840-A2 Process for the preparation of 2-(2-furyl) ethanol amine MONSANTO COMPANY (US) 1991-07-03 EP disclosed
EP-0435840-A2 Process for the preparation of 2-(2-furyl) ethanol amine MONSANTO COMPANY (US) 1991-07-03 EP disclosed
EP-0435840-A2 Process for the preparation of 2-(2-furyl) ethanol amine MONSANTO COMPANY (US) 1991-07-03 EP disclosed
US-4962212-A Process for the preparation of 2-(2-furyl)ethanol amine MONSANTO COMPANY (US) 1990-10-09 US disclosed
US-4962212-A Process for the preparation of 2-(2-furyl)ethanol amine MONSANTO COMPANY (US) 1990-10-09 US disclosed
US-4962212-A Process for the preparation of 2-(2-furyl)ethanol amine MONSANTO COMPANY (US) 1990-10-09 US disclosed
EP-0161801-A2 Perhydrothiazepine derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1985-11-21 EP disclosed