SCHEMBL4597339

SCHEMBL4597339

C=C(C)C(=O)OC(O)C(C)CC

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35900 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL11745073 0.82 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL8965966 0.81 TSHR (0.60) TSHRALDH1A1THRB
SCHEMBL2541289 0.80 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL22231053 0.80 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL6274834 0.79 TSHR (0.46) TSHRALDH1A1
SCHEMBL890775 0.79 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL1093435 0.79 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL23493903 0.78 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL22230941 0.78 TSHR (0.42) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699953-B2 A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE SEED CO., LTD. (JP) 2004-03-02 US claimed
US-20030130461-A1 Lens made f synthetic resin and process for producing the same SEED CO., LTD. (JP) 2003-07-10 US claimed
EP-1316820-A1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME Seed Co., Ltd. (JP) 2003-06-04 EP claimed
EP-1316820-B1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME SEED CO LTD (JP) 2008-01-16 EP disclosed
US-6699953-B2 A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE SEED CO., LTD. (JP) 2004-03-02 US disclosed
US-20030130461-A1 Lens made f synthetic resin and process for producing the same SEED CO., LTD. (JP) 2003-07-10 US disclosed
EP-1316820-A1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME Seed Co., Ltd. (JP) 2003-06-04 EP disclosed