Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281829 | 0.87 | SCN9A (0.76) | SCN9A | |
| SCHEMBL281474 | 0.86 | SCN9A (0.76) | SCN9A | |
| SCHEMBL281825 | 0.85 | SCN9A (0.77) | SCN9A | |
| SCHEMBL4597188 | 0.83 | SCN9A (0.71) | SCN9A | |
| SCHEMBL281265 | 0.82 | SCN9A (0.58) | SCN9A | |
| SCHEMBL282062 | 0.82 | SCN9A (0.64) | SCN9A | |
| SCHEMBL281486 | 0.79 | SCN9A (0.60) | SCN9A | |
| SCHEMBL14506555 | 0.79 | SCN9A (0.60) | SCN9A | |
| SCHEMBL14533501 | 0.79 | SCN9A (0.64) | SCN9A | |
| SCHEMBL27707826 | 0.78 | SCN9A (0.61) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877378-A2 | OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006113864-A2 | OXINDOLE COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-10-26 | — | — | WO | disclosed |