Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 18/20 | 0.58 |
| ▸ | PTGER4 | P35408 | 17/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057599 | 0.90 | PTGER4 (0.47) | PTGER2PTGER4 | |
| SCHEMBL1055159 | 0.83 | PTGER2 (0.80) | PTGER2PTGER4 | |
| SCHEMBL4086064 | 0.78 | PTGER4 (0.47) | PTGER2PTGER4 | |
| SCHEMBL15163146 | 0.78 | PTGER4 (0.46) | PTGER2PTGER4 | |
| SCHEMBL4087358 | 0.74 | PTGER4 (0.55) | PTGER2PTGER4 | |
| SCHEMBL1057453 | 0.73 | PTGER2 (0.65) | PTGER2PTGER4 | |
| SCHEMBL1057158 | 0.72 | PTGER2 (1.00) | PTGER2PTGER4 | |
| SCHEMBL1055986 | 0.71 | PTGER2 (1.00) | PTGER2PTGER4 | |
| SCHEMBL1057557 | 0.71 | PTGER2 (1.00) | PTGER2PTGER4 | |
| SCHEMBL1050702 | 0.71 | PTGER2 (1.00) | PTGER2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1439837-B1 | PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS | SERONO LAB (CH) | 2008-04-09 | — | — | EP | disclosed |