Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25130919 | 0.86 | TSHR (0.46) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL4597214 | 0.84 | TSHR (0.45) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL6678343 | 0.83 | ESR1 (0.40) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL17041300 | 0.82 | TSHR (0.43) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL4596352 | 0.81 | ATM (0.43) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL3820956 | 0.81 | ATM (0.43) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL29824350 | 0.78 | HTT (0.43) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL28880398 | 0.78 | HTT (0.43) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL15336461 | 0.78 | HTT (0.43) | TSHRHSD17B10KMT2AMAPTATM | |
| SCHEMBL4381767 | 0.77 | ATM (0.44) | TSHRHSD17B10KMT2AMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |