Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 17/20 | 0.78 |
| ▸ | USP7 | Q93009 | 11/20 | 0.76 |
| ▸ | USP47 | Q96K76 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1512480 | 0.88 | USP8 (1.00) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL1512378 | 0.87 | USP8 (1.00) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL4062211 | 0.83 | USP8 (0.54) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL4599919 | 0.83 | USP8 (0.61) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL4061070 | 0.83 | USP8 (0.61) | USP8USP7USP47RAB9ASMN1; SMN2 | |
| SCHEMBL14612220 | 0.81 | USP8 (0.81) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL4600361 | 0.79 | USP8 (0.49) | USP8USP7USP47 | |
| SCHEMBL1512485 | 0.73 | USP8 (1.00) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL30931160 | 0.73 | USP8 (1.00) | USP8USP7USP47MAPTRAB9A | |
| SCHEMBL1512515 | 0.73 | USP8 (0.92) | USP8USP7USP47MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912954-A2 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | Hybrigenics S.A. (FR) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017758-A2 | NOVEL CYSTEINE PROTEASE INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS | HYBRIGENICS SA (FR) | 2007-02-15 | — | — | WO | disclosed |