Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209429 | 0.91 | PPARG (0.65) | PPARGLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3207968 | 0.89 | PPARG (0.68) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL3202784 | 0.88 | PPARG (0.65) | PPARGLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5111589 | 0.88 | PPARG (0.67) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL3205204 | 0.88 | PPARG (0.72) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL5114186 | 0.87 | PPARG (0.66) | PPARGLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3204993 | 0.86 | PPARG (0.71) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL5120778 | 0.83 | PPARG (0.62) | PPARGLMNASMN1; SMN2 | |
| SCHEMBL3204436 | 0.82 | PPARG (0.55) | PPARGLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6901995 | 0.81 | SMN1; SMN2 (0.64) | PPARGLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |