⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600156 | 1.00 | — | — | |
| SCHEMBL4600148 | 1.00 | — | — | |
| SCHEMBL1891164 | 0.76 | — | — | |
| SCHEMBL1891166 | 0.76 | — | — | |
| SCHEMBL2465533 | 0.73 | — | — | |
| SCHEMBL2465534 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL28002765 | 0.73 | — | — | |
| SCHEMBL2173976 | 0.72 | — | — | |
| SCHEMBL2173973 | 0.72 | — | — | |
| SCHEMBL12341651 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910342-A1 | MULTICYCLIC SULFONAMIDE COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | Kalypsys, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007016354-A1 | MULTICYCLIC SULFONAMIDE COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| US-20070027184-A1 | Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease | KALYPSYS, INC. | 2007-02-01 | — | — | US | disclosed |
| US-5371097-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5364871-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0417751-A2 | New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| EP-0138464-B1 | 2-AMINO-5-HYDROXY-4-METHYLPYRIMIDINE DERIVATIVES | PFIZER INC. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0094191-B1 | ANTIULCER 2-GUANIDINO-4-(2-SUBSTITUTED-AMINO-4-IMIDAZOLYL)-THIAZOLES AND PROCESS THEREFOR | PFIZER INC. (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4673677-A | 2-AMINO-5-HYDROXY-4-METHYLPYRIMIDINE | PFIZER INC. (US) | 1987-06-16 | — | — | US | disclosed |
| US-4554276-A | ENZYME INHIBITORS, ANTIULCER AGENTS | PFIZER INC. (US) | 1985-11-19 | — | — | US | disclosed |
| US-4435396-A | FROM 2-AMINO-5-ACETYLOXAZOLE | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |