Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524825 | 0.91 | PPARG (0.61) | PPARG | |
| SCHEMBL4601365 | 0.84 | PPARG (0.53) | PPARG | |
| SCHEMBL4602112 | 0.80 | PPARG (0.62) | PPARG | |
| SCHEMBL3211067 | 0.80 | PPARG (0.62) | PPARG | |
| SCHEMBL3206838 | 0.79 | PPARG (0.48) | PPARG | |
| SCHEMBL3216002 | 0.79 | PPARG (0.63) | PPARG | |
| SCHEMBL3213630 | 0.78 | PPARG (0.63) | PPARG | |
| SCHEMBL4529260 | 0.78 | PPARG (0.61) | PPARG | |
| SCHEMBL4602424 | 0.75 | PPARG (0.57) | PPARGL3MBTL1LIPE | |
| SCHEMBL3209499 | 0.75 | PPARG (0.59) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |