SCHEMBL4600880

SCHEMBL4600880

CCOc1cc(NC(=O)c2ccc(OC)cc2)c(OCC)cc1[N+]#N

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
ALDH1A1 P00352 6/20 0.63
CYP1A2 P05177 3/20 0.63
CYP3A4 P08684 2/20 0.63
CYP2C9 P11712 2/20 0.63
CYP2C19 P33261 2/20 0.63
TSHR P16473 1/20 0.61
MAPK1 P28482 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
TP53 P04637 1/20 0.55
GAA P10253 1/20 0.55
HDAC1 Q13547 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
KDM4E B2RXH2 3/20 0.54
NPC1 O15118 1/20 0.54
LMNA P02545 2/20 0.53
ALOX12 P18054 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7031046 0.98 MAPT (0.66) MAPTMEN1KMT2AALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL11434618 0.98 MAPT (0.66) MAPTMEN1KMT2AALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL8412071 0.98 MAPT (0.66) MAPTMEN1KMT2AALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL8412068 0.97 MAPT (0.65) MAPTMEN1KMT2AALDH1A1CYP1A2
SCHEMBL7029827 0.96 MAPT (0.61) MAPTMEN1KMT2AALDH1A1CYP1A2
SCHEMBL31256869 0.88 MAPT (0.65) MAPTMEN1KMT2AALDH1A1CYP1A2
SCHEMBL3315675 0.88 MAPT (0.65) MAPTMEN1KMT2AALDH1A1CYP1A2
SCHEMBL7860242 0.87 MAPT (0.63) MAPTMEN1KMT2AALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL5941122 0.87 MAPT (0.64) MAPTMEN1KMT2AALDH1A1CYP1A2
Hydrochloric Acid SCHEMBL5941123 0.87 MAPT (0.64) MAPTMEN1KMT2AALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510246-B1 Method and apparatus for emulsification FUJIFILM CORP (JP) 2008-04-16 EP disclosed
US-6995273-B2 1H-pyrazolo[1,5-b]-1,2,4-triazole compound, coupler and silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2006-02-07 US disclosed
US-20050272604-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-12-08 US disclosed
US-20050260518-A1 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. 2005-11-24 US disclosed
EP-1598206-A2 Heat sensitive recording material and microcapsule FUJI PHOTO FILM CO., LTD. (JP) 2005-11-23 EP disclosed
EP-1598208-A2 Heat-sensitive recording material Fuji Photo Film Co., Ltd. (JP) 2005-11-23 EP disclosed
EP-1215644-B1 Adhesive recording paper FUJI PHOTO FILM CO LTD (JP) 2005-08-17 EP disclosed
US-6872687-B2 Thermosensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-03-29 US disclosed
US-20050056170-A1 Method and apparatus for emulsification FUJI PHOTO FILM CO., LTD. 2005-03-17 US disclosed
US-6864032-B2 Method for forming azo colorant using diazo compound and coupler having leaving group and recording material using the coupler FUJI PHOTO FILM CO., LTD. (JP) 2005-03-08 US disclosed
US-20020016260-A1 Method for forming azo colorant using diazo compound and coupler having leaving group and recording material using the coupler FUJIFILM CORPORATION (JP) 2002-02-07 US disclosed
US-6329116-B1 CYAN COUPLER AND A DIAZONIUM SALT COMPOUND, EXCELLENT SHELF LIFE, IMAGE LIGHT-RESISTANCE, IMAGE FIXING, EXCELLENT HUE AND COLOR DENSITY, PREFERABLY MICROENCAPSULATED IN POLYURETHANE OR POLYUREA FUJI PHOTO FILM CO., LTD. (JP) 2001-12-11 US disclosed
US-20010019806-A1 Azomethine dye precursor, image-forming material, and image-forming method FUJIFILM CORPORATION (JP) 2001-09-06 US disclosed
US-6248497-B1 LIGHT SENSITIVE AND HEAT SENSITIVE RECORDING IMAGES FUJI PHOTO FILM CO., LTD. (JP) 2001-06-19 US disclosed
US-6197725-B1 FOE DEVELOPING RED TO MAGENTA TO VIOLET, IMAGE STORABILITY AND IMAGE FIXING PROPERTY FUJI PHOTO FILM CO., LTD. (JP) 2001-03-06 US disclosed
EP-0930529-A1 Heat-sensitive recording material Fuji Photo Film., Ltd. (JP) 1999-07-21 EP disclosed
US-5925489-A CONTAINING DIAZONIUM SALT AND PYRROLOPYRIMIDINE COUPLER WHICH REACT WHEN HEATED TO DEVELOP VIOLET TO CYAN COLORS, IMAGE QUALITY AND STABILITY, SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1999-07-20 US disclosed
EP-0153616-B1 HEAT-SENSITIVE RECORDING MATERIALS KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-04-03 EP disclosed
US-4652512-A DIAZONIUM COMPOUND KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1987-03-24 US disclosed
EP-0153616-A2 Heat-sensitive recording materials KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-09-04 EP disclosed