Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 15/20 | 0.61 |
| ▸ | CPT2 | P23786 | 14/20 | 0.61 |
| ▸ | CPT1B | Q92523 | 12/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3572369 | 0.90 | CPT1A (0.74) | CPT1ACPT2CPT1B | |
| SCHEMBL30016042 | 0.89 | CPT2 (0.61) | CPT1ACPT2CPT1BMAPTSMN1; SMN2 | |
| SCHEMBL3569901 | 0.89 | CPT2 (0.61) | CPT1ACPT2CPT1BMAPTSMN1; SMN2 | |
| SCHEMBL30015196 | 0.89 | CPT1A (0.59) | CPT1ACPT2CPT1BMAPTKMT2A | |
| SCHEMBL3575184 | 0.89 | CPT1A (0.59) | CPT1ACPT2CPT1BMAPTKMT2A | |
| SCHEMBL3579488 | 0.87 | CPT1A (0.68) | CPT1ACPT2CPT1BMAPTKMT2A | |
| SCHEMBL30015611 | 0.87 | CPT1A (0.68) | CPT1ACPT2CPT1BMAPTKMT2A | |
| SCHEMBL3580510 | 0.86 | CPT2 (0.56) | CPT1ACPT2CPT1BMAPTKMT2A | |
| SCHEMBL3574595 | 0.83 | CPT2 (0.60) | CPT1ACPT2CPT1BMAPTKMT2A | |
| SCHEMBL30015821 | 0.82 | CPT1A (0.88) | CPT1ACPT2CPT1BMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926711-A1 | NOVEL HETEROBICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF LIVER CARNITINE PALMITOYL TRANSFERASE | F.HOFFMANN-LA ROCHE AG (CH) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007031429-A1 | NOVEL HETEROBICYCLIC DERIVATIVES USEFUL AS INHIBITORS OF LIVER CARNITINE PALMITOYL TRANSFERASE | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-22 | — | — | WO | disclosed |