Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600789 | 0.95 | HPGD (0.48) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4602102 | 0.91 | HPGD (0.49) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| Water SCHEMBL4601371 | 0.90 | HPGD (0.48) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4601130 | 0.89 | PPARG (0.49) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4601556 | 0.88 | HPGD (0.47) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4601774 | 0.87 | HPGD (0.49) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4600147 | 0.86 | HPGD (0.48) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4601418 | 0.85 | HPGD (0.51) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4600376 | 0.85 | HPGD (0.53) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL4601848 | 0.84 | HPGD (0.50) | HPGDLMNASMN1; SMN2ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |