Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.60 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.60 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.60 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336449 | 0.81 | SMN1; SMN2 (0.57) | SMN1; SMN2GAKRIPK2COQ8ANLK | |
| SCHEMBL4601893 | 0.81 | GRM4 (0.62) | SMN1; SMN2MAPTPOLBALDH1A1TDP1 | |
| SCHEMBL10061503 | 0.80 | MAPT (0.77) | MAPTPOLBHTTLMNAATM | |
| SCHEMBL379808 | 0.79 | CYP3A4 (0.60) | MAPTL3MBTL1HTTNPSR1ALDH1A1 | |
| SCHEMBL10061786 | 0.79 | MAPT (0.65) | SMN1; SMN2MAPTPOLBHTTLMNA | |
| SCHEMBL28579647 | 0.77 | KDM4E (0.59) | SMN1; SMN2MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL29886180 | 0.77 | KDM4E (0.59) | SMN1; SMN2MAPTPOLBALDH1A1MEN1 | |
| SCHEMBL8130849 | 0.76 | ABCB1 (0.58) | MAPTMAPK1ABCB1ABCG2KMT2A | |
| SCHEMBL20945452 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTPOLBHTTLMNA | |
| SCHEMBL11459070 | 0.75 | HTT (0.73) | SMN1; SMN2MAPTHTTLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |