Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSHR | P23945 | 9/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391454 | 0.87 | FSHR (0.56) | FSHRNPSR1TSHR | |
| SCHEMBL3391468 | 0.87 | FSHR (0.65) | FSHRHPGDNPSR1TSHR | |
| SCHEMBL3398312 | 0.84 | FSHR (0.55) | FSHRALDH1A1HPGDNPSR1POLB | |
| SCHEMBL3398323 | 0.84 | FSHR (0.64) | FSHRNPSR1TSHR | |
| SCHEMBL3394313 | 0.83 | FSHR (0.58) | FSHRHPGDNPSR1TSHR | |
| SCHEMBL3393370 | 0.83 | FSHR (0.58) | FSHRNPSR1HTTTSHR | |
| SCHEMBL4601275 | 0.82 | FSHR (0.57) | FSHRNPSR1TSHR | |
| SCHEMBL3393820 | 0.81 | FSHR (0.61) | FSHRNPSR1TSHR | |
| SCHEMBL4600825 | 0.81 | FSHR (0.68) | FSHRMAPTNPSR1TSHR | |
| SCHEMBL3433337 | 0.77 | FSHR (0.68) | FSHRMAPTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578727-B1 | TETRAHYDROQUINOLINE DERIVATIVES AND THEIR USE AS FSH RECEPTOR MODULATORS | ORGANON NV (NL) | 2008-04-16 | — | — | EP | disclosed |