Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636534 | 0.83 | PPARG (0.60) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4601962 | 0.82 | PPARG (0.58) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4601769 | 0.81 | PPARG (0.58) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4602636 | 0.80 | PPARG (0.56) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4601080 | 0.80 | PPARG (0.61) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4602576 | 0.79 | PPARG (0.61) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| Water SCHEMBL4600773 | 0.79 | PPARG (0.51) | PPARG | |
| SCHEMBL4601402 | 0.79 | PPARG (0.56) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4601809 | 0.78 | PPARG (0.60) | PPARGLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL4601583 | 0.78 | PPARG (0.63) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |