Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602710 | 0.90 | MAPK14 (0.57) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL2950992 | 0.86 | MAPK14 (0.58) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL4603694 | 0.85 | MAPK14 (0.53) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL4615972 | 0.85 | MAPK14 (0.55) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL6142656 | 0.84 | MAPK14 (0.66) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL2960045 | 0.84 | MAPK14 (0.67) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL4604812 | 0.84 | MAPK14 (0.57) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL4603053 | 0.84 | MAPK14 (0.53) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL4604376 | 0.82 | PRKAA2 (0.56) | MAPK14MAPK11MAPTMAPK13MAPK12 | |
| SCHEMBL4602180 | 0.82 | MAPK14 (0.53) | MAPK14MAPK11MAPTMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761520-B1 | KINASE INHIBITORS | LILLY CO ELI (US) | 2008-07-09 | — | — | EP | disclosed |