SCHEMBL4601410

SCHEMBL4601410

CCCN(CCc1sccc1-c1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl)S(=O)(=O)OC(N)=O

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4601583 0.79 PPARG (0.63) PPARG
SCHEMBL4601809 0.77 PPARG (0.60) PPARG
SCHEMBL4602596 0.76 PPARG (0.59) PPARG
Water SCHEMBL4600773 0.76 PPARG (0.51) PPARG
SCHEMBL4601402 0.76 PPARG (0.56) PPARG
SCHEMBL4601080 0.75 PPARG (0.61) PPARG
SCHEMBL4613200 0.75 PPARG (0.55) PPARG
SCHEMBL4601962 0.75 PPARG (0.58) PPARG
SCHEMBL4601769 0.75 PPARG (0.58) PPARG
SCHEMBL4614556 0.74 PPARG (0.52) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP disclosed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO disclosed