SCHEMBL460189

SCHEMBL460189

Nc1nc2c(nnn2[C@@H]2O[C@H](CO)C(O)C2O)c(=O)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 2/20 0.67
▸ MEN1 O00255 1/20 0.53
▸ KMT2A Q03164 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ TLR7 Q9NYK1 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ HPGD P15428 1/20 0.47
▸ ADA P00813 1/20 0.47
▸ HINT1 P49773 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1100799 1.00 PNP (0.67) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL7057522 1.00 PNP (0.67) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL17198373 0.91 PNP (0.55) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL18519991 0.90 PNP (0.54) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL462463 0.86 PNP (0.52) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL28642522 0.86 PNP (0.52) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL28603432 0.85 PNP (0.52) PNPMEN1KMT2ACYP3A4MAPT
SCHEMBL6041233 0.84 NT5E (0.57) PNP
SCHEMBL8630096 0.84 NT5E (0.57) PNP
SCHEMBL8649743 0.82 PNP (0.47) PNPMEN1KMT2ACYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3642 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139030-A1 CHIMERIC PROTEINS FOR TREATING CUTANEOUS INFLAMMATION SHATTUCK LABS INC (US) 2026-05-21 — — US claimed
EP-4705481-A2 CIRCULAR RNA COMPOSITIONS AND METHODS Orna Therapeutics, Inc. (US) 2026-03-11 — — EP claimed
US-20260049338-A1 METHODS AND PRODUCTS FOR TRANSFECTING CELLS FACTOR BIOSCIENCE INC (US) 2026-02-19 — — US claimed
US-20250345406-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY SHATTUCK LABS INC (US) 2025-11-13 — — US claimed
US-20250325494-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-10-23 — — US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 — — EP claimed
US-12384740-B2 Cationic lipids and transfection methods FACTOR BIOSCIENCE INC. (US) 2025-08-12 — — US claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 — — WO claimed
US-20250188013-A1 LIPID COMPOUND AND USE THEREOF THEMEDIUM THERAPEUTICS CO., LTD. (CN) 2025-06-12 — — US claimed
WO-2025122721-A1 CHIMERIC PROTEINS AND USES THEREOF SHATTUCK LABS, INC. (US) 2025-06-12 — — WO claimed
WO-2009143454-A2 COMBINATION ANTITUMOR THERAPY KEREOS, INC. (US) 2009-11-26 — — WO claimed
US-20080120733-A1 Rnai-Based Method for Selecting Transfected Eukaryotic Cells GBF-GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG (DE) 2008-05-22 — — US claimed
EP-1759004-A1 RNAI-BASED METHOD FOR SELECTING TRANSFECTED EUKARYOTIC CELLS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2007-03-07 — — EP claimed
WO-2005123925-A1 RNAI-BASED METHOD FOR SELECTING TRANSFECTED EUKARYOTIC CELLS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2005-12-29 — — WO claimed
EP-1607482-A1 RNAi-based methods for selection of transfected eucaryotic cells GBF-GESELLSCHAFT FÜR BIOTECHNOLOGISCHE FORSCHUNG MBH (DE) 2005-12-21 — — EP claimed
EP-1499187-A2 IMMUNOSTIMULATORY G,U-CONTAINING OLIGORIBONUCLEOTIDES Coley Pharmaceutical GmbH (DE) 2005-01-26 — — EP claimed
US-20030232074-A1 For stimulating immune activation; for screening immunostimulatory compounds COLEY PHARMACEUTICAL GMBH (DE) 2003-12-18 — — US claimed
WO-2003086280-A2 IMMUNOSTIMULATORY G,U-CONTAINING OLIGORIBONUCLEOTIDES COLEY PHARMACEUTICAL GMBH (DE) 2003-10-23 — — WO claimed
EP-1194168-A2 METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2002-04-10 — — EP claimed
WO-2000078941-A2 METHODS AND PRODUCTS FOR MANIPULATING UNCOUPLING PROTEIN EXPRESSION UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2000-12-28 — — WO claimed
Send feedback