Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ADH1C | P00326 | 2/20 | 0.41 |
| ▸ | ADH1A | P07327 | 2/20 | 0.41 |
| ▸ | ADH4 | P08319 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871631 | 1.00 | TSHR (0.44) | TSHRADH1CADH1AADH4EPHX1 | |
| SCHEMBL6850245 | 0.97 | TSHR (0.40) | TSHRADH1CADH1AADH4EPHX1 | |
| SCHEMBL28832704 | 0.74 | TSHR (0.44) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL27255307 | 0.74 | TSHR (0.44) | TSHRTHRBCES2CTSLCTSB | |
| SCHEMBL28407024 | 0.74 | TSHR (0.44) | TSHRTHRBCES2CTSLCTSB | |
| Octane SCHEMBL8523622 | 0.73 | TSHR (0.56) | TSHRADH1CADH1AADH4EPHX1 | |
| Heptane SCHEMBL1975945 | 0.73 | TSHR (0.56) | TSHRADH1CADH1AADH4EPHX1 | |
| Decane SCHEMBL27095057 | 0.73 | TSHR (0.56) | TSHRADH1CADH1AADH4EPHX1 | |
| Hexadecane SCHEMBL28158362 | 0.73 | TSHR (0.56) | TSHRADH1CADH1AADH4EPHX1 | |
| Dodecane SCHEMBL28219621 | 0.73 | TSHR (0.56) | TSHRADH1CADH1AADH4EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694748-B1 | METHOD OF MODIFYING A FLUOROPOLYMERIC SUBSTRATE AND COMPOSITE ARTICLES THEREBY | 3M INNOVATIVE PROPERTIES CO (US) | 2008-04-23 | — | — | EP | disclosed |
| US-7273531-B2 | Method of modifying a fluoropolymeric substrate and composite articles thereby | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-25 | — | — | US | disclosed |
| US-20050092429-A1 | Method of modifying a fluoropolymeric substrate and composite articles thereby | 3M INNOVATIVE PROPERTIES COMPANY | 2005-05-05 | — | — | US | disclosed |