Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211203 | 0.90 | PPARG (0.55) | PPARG | |
| SCHEMBL3217588 | 0.90 | PPARG (0.59) | PPARGCNR1CNR2 | |
| SCHEMBL3206932 | 0.83 | PPARG (0.61) | PPARGCNR1CNR2 | |
| SCHEMBL3217121 | 0.81 | PPARG (0.67) | PPARG | |
| SCHEMBL3219476 | 0.81 | PPARG (0.59) | PPARGCNR1CNR2 | |
| SCHEMBL3202441 | 0.78 | PPARG (0.56) | PPARGCNR1CNR2 | |
| Water SCHEMBL3217807 | 0.78 | PPARG (0.70) | PPARG | |
| Water SCHEMBL3217812 | 0.78 | PPARG (0.70) | PPARG | |
| SCHEMBL3221830 | 0.76 | PPARG (0.82) | PPARG | |
| SCHEMBL3202465 | 0.76 | PPARG (0.58) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |