Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 10/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.56 |
| ▸ | ITGAL | P20701 | 10/20 | 0.56 |
| ▸ | ECE1 | P42892 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155569 | 0.82 | ITGB2 (0.54) | ITGB2ICAM1ITGALECE1HDAC3 | |
| SCHEMBL4602372 | 0.78 | ITGB2 (0.57) | ITGB2ICAM1ITGALECE1HDAC3 | |
| SCHEMBL14159181 | 0.78 | ITGB2 (0.46) | ITGB2ICAM1ITGALECE1CDK4 | |
| SCHEMBL14161518 | 0.78 | ITGB2 (0.45) | ITGB2ICAM1ITGALECE1HDAC3 | |
| SCHEMBL16007167 | 0.78 | ITGB2 (0.43) | ITGB2ICAM1ITGALECE1HDAC3 | |
| SCHEMBL14811840 | 0.78 | ITGB2 (0.43) | ITGB2ICAM1ITGALECE1HDAC3 | |
| SCHEMBL14091954 | 0.77 | ITGB2 (0.45) | ITGB2ICAM1ITGALECE1CDK4 | |
| SCHEMBL14161463 | 0.77 | ITGB2 (0.45) | ITGB2ICAM1ITGALECE1CDK4 | |
| SCHEMBL4601042 | 0.77 | CDK4 (0.53) | ITGB2ICAM1ITGALECE1HDAC3 | |
| SCHEMBL5151054 | 0.77 | ITGB2 (0.54) | ITGB2ICAM1ITGALHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912970-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007017289-A2 | ACYLTRYPTOPHANOLS FOR FERTILITY CONTROL | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-02-15 | — | — | WO | disclosed |