SCHEMBL4602373

SCHEMBL4602373

CCCCCS(=O)(=O)NC(=O)/C=C/c1ccc(OC(C)COCCOCC)cc1Oc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3202756 0.91 PPARG (0.84) PPARG
SCHEMBL3202740 0.91 PPARG (0.84) PPARG
SCHEMBL3221903 0.90 PPARG (1.00) PPARG
SCHEMBL3221915 0.90 PPARG (1.00) PPARG
SCHEMBL3206626 0.86 PPARG (0.96) PPARG
SCHEMBL3206642 0.86 PPARG (0.96) PPARG
SCHEMBL3211431 0.86 PPARG (1.00) PPARG
SCHEMBL4523356 0.86 PPARG (1.00) PPARG
SCHEMBL3211421 0.86 PPARG (1.00) PPARG
SCHEMBL4523353 0.86 PPARG (1.00) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP claimed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO claimed
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP disclosed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO disclosed