Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891234 | 0.95 | — | — | |
| SCHEMBL7705371 | 0.78 | HDAC1 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL22343804 | 0.77 | — | — | |
| SCHEMBL18950082 | 0.76 | EPHX1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| SCHEMBL11639864 | 0.76 | EPHX1 (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC11 | |
| Dimethylamine SCHEMBL11340752 | 0.74 | PAOX (0.60) | HDAC3HDAC1HDAC2PAOXMMP1 | |
| SCHEMBL15456235 | 0.74 | — | — | |
| SCHEMBL4864289 | 0.74 | — | — | |
| SCHEMBL14907230 | 0.73 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL749123 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435363-B1 | Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts | AIR PROD & CHEM (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1435365-B1 | Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams | AIR PROD & CHEM (US) | 2007-06-13 | — | — | EP | disclosed |
| US-7192990-B2 | Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7189765-B2 | Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-6762211-B1 | FORMING POROUS, OPEN, DIMENSIONALLY STABLE FOAM; IMPARTING COMPRESSABILITY AND SHRINKAGE RESISTANCE | AIR PRODUCTS AND CHEMICALS, INC. | 2004-07-13 | — | — | US | disclosed |
| US-20040132851-A1 | Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl and fatty carboxylic acids | AIR PRODUCTS AND CHEMICALS, INC. | 2004-07-08 | — | — | US | disclosed |
| US-20040132847-A1 | TERTIARY AMINO ALKYL AMIDE POLYURETHANE CATALYSTS DERIVED FROM LONG CHAIN ALKYL AND FATTY CARBOXYLIC ACIDS | EVONIK DEGUSSA GMBH (DE) | 2004-07-08 | — | — | US | disclosed |
| US-20040132850-A1 | Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. | 2004-07-08 | — | — | US | disclosed |
| US-20040132849-A1 | Physical properties of polyurethane foams using tertiary amino alkyl amide catalysts | AIR PRODUCTS AND CHEMICALS, INC. | 2004-07-08 | — | — | US | disclosed |
| EP-1435363-A2 | Improving the physical properties of polyurethane foams using tertiary amino alkyl amide catalysts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1435365-A2 | Tertiary amino alkyl amide catalysts for improving the physical properties of polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-07-07 | — | — | EP | disclosed |
| EP-1435364-A2 | Tertiary amino alkyl amide polyurethane catalysts derived from long chain alkyl or fatty carboxylic acids | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-07-07 | — | — | EP | disclosed |
| US-6759447-B1 | MINIMIZING SHRINKAGE; IMPROVING DIMENSIONAL STABILITY | AIR PRODUCTS AND CHEMICALS, INC. | 2004-07-06 | — | — | US | disclosed |
| US-6737446-B1 | POROSITY, OPENNESS; DIMENSIONAL STABILITY | AIR PRODUCTS AND CHEMICALS, INC. | 2004-05-18 | — | — | US | disclosed |