SCHEMBL4602684

SCHEMBL4602684

CCCCCCCCCCCCCC=CC(=O)NN

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.53
SOAT1 P35610 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2C19 P33261 2/20 0.53
MEN1 O00255 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
KMT2A Q03164 1/20 0.53
PSMB11 A5LHX3 1/20 0.53
PSMA7 O14818 1/20 0.53
PSMB1 P20618 1/20 0.53
PSMA1 P25786 1/20 0.53
PSMA2 P25787 1/20 0.53
PSMA3 P25788 1/20 0.53
PSMA4 P25789 1/20 0.53
PSMB8 P28062 1/20 0.53
PSMB9 P28065 1/20 0.53
PSMA5 P28066 1/20 0.53
PSMB4 P28070 1/20 0.53
PSMB6 P28072 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18322819 0.92 PSMB11 (0.44) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL18322820 0.92 PSMB11 (0.44) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL28967967 0.87 CNR1 (0.63) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL5520146 0.86 CNR1 (0.61) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL5520144 0.86 CNR1 (0.61) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL16658735 0.82 PSMB11 (0.54) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL16658737 0.82 PSMB11 (0.54) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL5794871 0.82 PSMB11 (0.54) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL8089119 0.82 PSMB11 (0.54) FAAHSOAT1CYP1A2CYP2C19MEN1
SCHEMBL16658738 0.82 PSMB11 (0.54) FAAHSOAT1CYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1543096-B1 ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS CHEMTURA CORP (US) 2008-04-30 EP disclosed
EP-1543096-A1 ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS Uniroyal Chemical Company, Inc. (US) 2005-06-22 EP disclosed
WO-2004029183-A1 ALKYL-SUCCINHYDRAZIDE ADDITIVES FOR LUBRICANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2004-04-08 WO disclosed
US-6706671-B2 A LUBRICANT, AND 4-ALKYL-1,2-DIHYDROPYRIDAZINE-3,6-DIONES, WHICH IS ASHLESS AND NONPHOSPHORUS CONTAINING ANTIWEAR, ANTIFATIGUE AND EXTREEM PRESSURE ADDITIVE UNIROYAL CHEMICAL COMPANY, INC. 2004-03-16 US disclosed
US-20030104953-A1 A lubricant, and 4-alkyl-1,2-dihydropyridazine-3,6-diones, which is ashless and nonphosphorus containing antiwear, antifatigue and extreem pressure additive UNIROYAL CHEMICAL COMPANY, INC. 2003-06-05 US disclosed